Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p487 | Preclinical and ex vivo imaging | ECTS2016

The CAM assay for human bone regeneration evaluation: the potential of Laponite® clay gel for growth factor delivery ex vivo

Moreno-Jimenez Ines , Hulsart-Billstrom Gry , Lanham Stuart A , Kanczler Janos M , Evans Nicholas D , Oreffo Richard O C

An increasing number of biomaterials are in development, seeking to mimic the natural cascade of events during fracture repair. However, these biomaterials need to be rigorously tested prior to clinical application. In vitro testing lacks the physiological environment, while in vivo studies do not always predict the patient response. Here we hypothesize that the chorioallantoic membrane (CAM) assay can be used to culture human living bone and we aim to examin...